The Clinical Vector Core includes dedicated facilities for the manufacturing of clinical and non-clinical AAV and LV vectors in support of clinical trials. Facility systems, manufacturing equipment, and aseptic fill and finish operations are validated and compliant with current Good Manufacturing Practices (cGMP).

Specialized manufacturing equipment includes:

  • Large and small-scale Tangential Flow Filtration (TFF) units
  • Microfluidizers
  • Chromatography systems
  • Centrifuges and ultracentrifuges
  • Biosafety cabinets
  • Freezers and refrigerators
  • CO2 incubators

Quality Control Laboratory includes equipment for:

  • Environmental monitoring plates and bioburden
  • Optical density
  • pH
  • Conductivity
  • ELISA
  • Western Blot
  • Quantitative PCR
  • Digital PCR